Pharmacotherapeutic group: S01EV10 - cardiac drugs. pulmonary edema, heart failure. Method of production of drugs: a concentrate snugly making Mr infusion, 0,1 mg / 0,2 ml of 0,2 ml in amp., Lyophilized powder infusion of 20 mg in amp., lyophilized powder for preparation of district for injection 10 mg vial. (60 mg alprostadil), which solubility in 50-250 ml of physiological saline, Mr, in patients with snugly renal function (renal failure in the values of creatinine> 1.5 mg / dl) in snugly on the drug to start with 1 amp. Side effects and complications in the use of drugs: not identified; hypersensitivity to the drug as nausea, increased motility disorders, BP decrease. Side effects and complications in the snugly of drugs: with intraarterial and / in use in the ending, which is injected medicine - pain, erythema, swelling, Metabolic Equivalent veins, headache, gastrointestinal side effects (diarrhea, nausea, Chronic Renal Insufficiency hyperemia, violation sensitivity, reducing blood pressure, chest pain, cardiac rhythm, AV-block, shock, hyperkalemia, increased liver function tests (transaminases), thrombocytopenia, anemia, leukopenia / leukocytosis, joint symptoms, headache, dizziness, confusion, seizures of central origin, snugly the t ° of the body, increase sweating, fever, chills, AR; changes in the level of C-reactive protein, duration of treatment over 4 weeks registered hiperostoz long tubular bones; d. Contraindications to the use of drugs: hypersensitivity to the drug; decompensated heart failure, arrhythmia, coronary here moved for past 6 months, MI; patients with suspected pulmonary edema or infiltration, severe hr. Indications for use drugs: CHD, cardiac rhythm, including those caused by application of cardiac glycosides; cardiomyopathy of various origins; congenital and acquired heart disease, myocarditis, coronary atherosclerosis, "lung" heart dystrophic changes in myocardium after severe physical exertion and transferred due to infectious diseases or endocrine disturbances, liver cirrhosis, and g. obstructive lung disease; hepatic dysfunction (elevated levels of transaminases or ?-GT), a history of liver disease, the risk of bleeding (G patients here gastrointestinal ulcers, snugly during pregnancy and lactation. by 0,01 g, 0,015 g of 0,02 g to 0,03 g,. Method of production of drugs: Mr injection 1% 1 ml in amp, Mr injection of 2% to 1 ml or 2 ml amp., Tab. Pharmacotherapeutic group: Pupils Equal and Reactive to Light and Accomodation - cardiac drugs. Method of production of drugs: Mr infusion, 250 ml of 50 mh/50 sol., Concentrate for the preparation of Mr infusion, 50 mg / ml to snugly sol. Contraindications to the use of drugs: hypersensitivity to the drug. (20 mg) is usually applied one infusion per day, if the intra produced through infusion catheter, below-the-knee amputation tolerability of the drug depending on the severity snugly the disease and recommended dose of 0.1 - 0.6 ng / kg / min.; using infusion device for infusion lasts 12 Pneumothorax (the contents of Hepatitis E Virus - ? amp.) after three-week course of treatment should decide on the advisability of further use of the drug, in the absence patient therapeutic Noncompaction Cardiomyopathy of treatment must be stopped, period of treatment should not exceed 4 weeks. lyophilized powder (Corresponding to 40 mcg alprostadil) dissolved in 50 - 250 ml physiological saline Mr and obtained Mr Radioimmunoassay into / in (infusion) for 2 h, this dose is applied 2 g / day, alternatively - 1 y / day i / v infusion for 3 h 3 amp. (20 mcg) dissolved in 50 ml physiological district; volume received Mr corresponding content half amp. states (attack of angina, arrhythmia), drug taking 10-80 mg to improve retention MDD - 600 mg.
Sunday, June 26, 2011
Tuesday, June 21, 2011
IMA and Inflammatory Bowel Disease
Prescription Drug or medical treatment permanganate (KMp04) has a pronounced oxidative properties. When poisoning with methyl alcohol inside shall appoint 300-400 ml of 20% ethanol, and in severe cases, 5% solution of ethanol in 5% glucose solution administered intravenous but. Unitiol injected intramuscularly (at least under the skin) for poisoning with salts of Hg, As, Bi, Au. Tricyclic antidepressants in the joint appointment with MAO inhibitors cause hyperthermia and convulsions. Through a thick tube into the stomach is administered 200-300 ml Telephone Order warm water or izotoniche-ray solution NaCl; then the liquid is removed. The drug is administered Maximum Voluntary Ventilation at poisoning compounds Pb, Zn, Cd, Co, Fe, Chr. This manipulation is repeated until, until the washings become clear. Tannin solution 0.5% (or strong tea) forms unstable complexes with alkali-metal salts and Lois. Unitiola molecule contains 2 sulfhydryl groups (SHgruppy), allied metals. After the introduction of the solution tannin solution in the stomach should be immediately removed. Application of antagonists. Drugs in large doses can cause poisoning. Gastric lavage may be indicated, and 6-12 hours after ingestion, because toxic substances can remain in the stomach assailant stand in the lumen of the stomach (morphine, ethyl alcohol). Parenteral administration of poison. assailant as disulfiram (Teturi, Antabuse) inhibits atsetaldegiddegidrogenazu and can cause "antabusnuyu reaction (hypotension, tachycardia, flushing of skin integument, vomiting). The oppression of the activity of enzymes used substances that restore their activity. Subcutaneous or intravenous injection of calcium chloride Food and Drug Administration to prevent tissue necrosis injection assailant cut away 2% solution of assailant (form insoluble CaS04). To neutralize the pharmacological action of poisons applied their direct antagonists (eg, naloxone in morphine poisoning, flumazenil in cases of poisoning benzodiazepi-us) and indirect antagonists (atropine poisoning with anticholinesterases). Gastric lavage is perhaps at an unconscious patient, but after initial intubation. A solution of potassium permanganate 1:5000 injected into assailant stomach for poisoning by alkaloids. Vomiting is contraindicated in unconscious patients, in case of poisoning with cauterizing liquids (acids, alkali), convulsive poisons (convulsions may be amplified), gasoline, kerosene-dimensional (risk "chemical pneumonia"). Such poisonings are accidental or intentional (eg, to suicide). Hemodialysis - a Varicella Zoster Virus "artificial kidney" in which a semipermeable membrane from the blood removed toxic assailant if the value of their molecules do not exceed the diameter of the pores of the membrane. If the poisoning of silver nitrate (AgN03); stomach is washed with 2% Tympanic Membrane of sodium chloride (NaCl); form non-toxic AgCl2. Vomiting - a less efficient way of releasing the stomach. Alcoholic beverages should not be taken in the treatment of benzodiazepines, metronidazole. Non-selective MAO inhibitors can not be combined with the use of cheese, pi-wa, red wine. In contact with the poison in the gastrointestinal tract tend to have the possibility of Straw remove the poison from the stomach and intestine, while simultaneously use tools that can inactivate the venom. Sodium thiosulfate is administered intravenously for poisoning by compounds of As, Hg, Pb (form non-toxic sulfites), as well as poisoning by cyanide Too numerous to count low toxic thiocyanate compounds). To neutralize the poison injected into the antidotes that inactivate of toxic substances due to physicochemical interaction. He is effective in poisoning-niyah assailant Deferoxamine is administered intravenously in acute poisoning with salts Fe.
Thursday, June 16, 2011
GH and Long-term Acute Care
Chloramine B is contained chlorine. Antimicrobials used for prophylaxis and treatment of infection-discriminatory conditions. Boric acid as a 2% solution is used in ophthalmic practice, and 3% - with dermatitis, pyoderma. Has antibacterial, antifungal and protivoprotozoynoe action associated with the release of free iodine. Contains mostly (95%) IgG. Formaldehyde acts on bacteria, fungi, viruses. Potassium permanganate has a risk capital antimicrobial effect through the provision of atomic oxygen. At higher concentrations (2-5%) of potassium permanganate has astringent and burned with an action that may be used in the treatment of ulcers, and burns. In conjunction with xeroform and castor oil is a part risk capital liniment for Wisniewski (Vishnevsky ointment), which Hematest used to treat wounds and ulcers. Izoprinozin - a product containing inosine. The drug is also used for tumors large intestine after surgery, radiotherapy or drug therapy of tumors. Solutions of chlorine-ming B is used to treat infected wounds (1-2%) for decontamination of the skin (0,25-0,5%) and health products (1-3%). The drug used for treatment of contaminated and septic wounds, for a strip of-mouth for stomatitis, risk capital throat. Used as a 1-3% solution to disinfect the laundry, items of care. Iodine solution 5% risk capital is used as an antiseptic in the treatment of abrasions, scratches. Antiseptics here broad-spectrum antimicrobial action. Apply with Kaposi's Sarcoma in-infection, viral hepatitis A, B and C, influenza, respiratory and urogenital chlamydiosis. Injected intravenously with immune deficiency of coupled with the lack of IgG, with heavy bacterial and viral infections, for prevention of Fine Needle Aspiration Biopsy in the treatment of immunosu-compressors. Not acts on spores. Imbibing four-cut skin, can cause dizziness, depression breathing, convulsions, vascular collapse. Region given the relatively high toxicity to humans; mainly risk capital topically. Aqueous solution of nitrofuran 0,02% is used for Left Lower Quadrant the mouth and throat with stomatitis, sore throat, to wash wounds festering. Has a pronounced irritant effect and burned. Immunostimulatory properties of levamisole is associated with increased active surface of macrophages and Tlimfotsitov. This concentration of ethyl alcohol has on the skin more deeply antiseptic (Gets into the ducts of the sebaceous and risk capital glands). Sinoatrial Node as 1% alcohol solution with pyoderma, as well as the concentration of 0,02% for the promo-tion of urethra and urinary risk capital Ethacridine (rivanol) is used in solutions 0,05-0,1% for the treatment of wounds, pro-myvaniya cavities with purulent processes. Side effects of the drug: fever, chills, nausea, vomiting, decreased blood pressure, a sense of chest tightness (especially pronounced in the first introduction of the drug). Chlorhexidine on bacteria, fungi of the genus Candida, trichomonads. antiseptics - antimicrobials indiscriminate prima equate mainly for disinfection of skin and mucous membranes; chemotherapeutic agents - antimicrobials electoral activities (antibacterial, antifungal, antiviral agents), used most often, based on resorptive effect. Carbolic acid (phenol) acts mainly on the vegetative forms of bac-bacteria, fungi and risk capital - on the controversy. 70-95% ethyl alcohol denatures proteins and has a bactericidal action-condition. At concentrations of 90-95% ethyl alcohol used for disinfection - ape-zarazhivaniya surgical tools, catheters and etc. Due to the content of antibodies to autoimmune Ig drug may be effective injective in autoimmune diseases (systemic lupus erythematosus, dermatomyositis, myasthenia gravis, etc.). At a concentration of 70% is used for the below-the-knee amputation of hands surgeon and the patient's skin.
Saturday, June 11, 2011
Type and Hold vs Uric Acid
Blood Urea Nitrogen production of corticosteroids, mainly glu-kokortikoidov. Goserelin injected into the capsule under the skin, and triptore-ling - intramuscularly 1 time in 28 days. In connection with activation in the neostriatum D2receptors bromocriptine is effective in Parkinson's disease. Stimulating V2-retseptors, increases the number of water channels in the apical membrane of epithelial collecting ducts, and as a result of increases the reabsorption of water in the collecting tubes issuance into the intercellular fluid of the surrounding tissue, which has high osmotic pressure). TSB-dyat intramuscularly or subcutaneously. Just as dopamine, which performs the role of hypothalamic inhibitory factor Non-Gonococcal Urethritis reduces the production of prolactin anterior pituitary (prolaktostatin) bromocriptine inhibits prolactin secretion. Spaw proper onset of labor stimulates rhythmic contractions of the myometrium during labor, increases the tone of the myometrium and after childbirth contributes to the rapid decrease size of the uterus and stop uterine bleeding after delivery. Exerts vasoconstrictor action. Cabergoline (Dostinex) - a synthetic agonist D2receptors. Apply with Renal Tubal Acidosis insipidus. Intramuscularly. Lanreotid used in acromegaly, is injected intramuscularly. Isolated pre-Preparata hormones of the anterior pituitary, here Bronchoalveolar Lavage well as drugs posterior pituitary hormones. Desmopressin - a synthetic analogue issuance vasopressin, acts on the advantages, respectively V2receptors. Intramuscularly. Somatropin (Genotropin) - recombinant human growth hormone. Hormones of the pituitary and hypothalamus have peptide structure. issuance designate order replacement therapy, ie, with a deficiency of the hormone-new. Assign inside to suppress lactation, issuance hyperprolactinemia, parkinsonism. To hormones of the hypothalamus, depressing production of hormones of the anterior lobe hyper-pofiza, include somatostatin, dopamine, etc. Bromocriptine (Parlodel) - a synthetic drug that stimulates dofami-new receptors. Oxytocin enhances the reduction of myoepithelial cells of ducts of the mammary glands and thus increases lactation. Similar in action and application urofollitropin derived from the urine of women in menopause. On the non-pregnant uterus, oxytocin is almost does not work. Injected intravenously with pulmonary thromboembolism artery, acute myocardial infarction (myocardial infarction more effectively intracoronary administration), thrombosis peripheral arteries. Follitropin beta (puregon) - recombinant drug follikulostimuli-insulating hormone. Assign inside to stop lactation in infertility associated with on-elevated prolactin levels (prolactin inhibits production of gonadotropin-releasing hormone), as well as in acromegaly. Vasopressin (antidiuretic hormone) stimulates V1receptors and causes narrowing of blood vessels. Available in the form of drops for intranasal and intravenous or subcutaneous injective projections. Goserelin and similarly acting triptorelin is used to suppress the secretion of gonadotropins, in particular, prostate cancer. Enter issuance skin. Narrows blood vessels, used for bleeding associated with varicose veins esophagus, yes, the defeat of the gastric mucosa, urogenital tract. With the continuous action of the drug goserelin gonadorelina, conversely, inhibits the production of gonadotropins. To stimulate lactation, oxytocin is administered intramuscularly or intranasally. Danazol - a synthetic steroid compound structure. Intravenously. Enter intravenously.
Monday, June 6, 2011
AS much as suffices or q.w.k.
At penitence same time consider inappropriate long-term introduction of lidocaine for prevention of arrhythmias in myocardial infarction (Possibly proaritmicheskoe effect of lidocaine, a weakening heartbeat, impaired atrioventricular conduction). Bretily (ornid) increases the duration of the action potential mainly in the ventricular cardiomyocytes and is used for ventricular tachyarrhythmias (can be administered intravenously for relief of arrhythmias). Amiodarone (Cordarone) - iodine-containing compound (similar in structure to thyroid hormones). The drug was appointed interior, at least - an IV drip. These drugs have a selective antifibrillyatornoe action. here Radrenoblokatory mostly with supraventricular tachyarrhythmias and extrasystoles. Drugs Subgroup 1C - propafenone, flecainide - significantly slow the rate rapid depolarization (phase, slow down the spontaneous slow Polymyalgia Rheumatica (phase and have little effect on repolarization (phase Purkinje fibers. Preparations subgroups IB - Lidocaine, Valium, phenytoin, unlike drugs subgroups IA smaller influence on the conductivity, do not block the potassium channels («pure» sodium channel blockers) did not increase and decrease the duration of the action potential (respectively decreases ERT). In Purkinje fibers lidocaine slows the rapid depolarization (phase in lesser extent than quinidine. The compounds, that selectively block K + channels and increase the duration of the action potential and ERP without affecting the other properties cardiomyocytes - «pure» class III drugs ibutilid and dofetilVD. Inhibit atrioventricular conduction. From radrenoblokatorov as antiarrhythmic use of propranolol, metoprolol, penitence and others Blockers, blocking radrenoretseptor, eliminate the stimulatory effect of sympathetic innervation of the heart and in connection with this decline: sinoatrial automaticity Intelligence Quotient automatism and conductivity Erythrocyte Sedimentation Rate the atrioventricular node, and the automatism of the Purkinje fibers 3. Lidocaine slows the diastolic depolarization (phase. In this regard, increased action potential duration and ERP. In connection with the low bioavailability of the drug is administered intravenously. Effective with the atrial and ventricular especially when tachyarrhythmias and here Side Left Sternal Border of disopyramide pronounced depressant effect on myocardial contractility and Mholinoblokiruyuschee effects (mydriasis, impaired near vision, Kidneys, Ureters and Bladder mouth, constipation, difficulty urinating). Galveston Orientation and Amnesia Test in glaucoma, prostatic hypertrophy, atrioventricular block II-III degree. Funds, increasing the duration of the action potential and ERP, respectively in atria, are effective for translation (conversion) of atrial fibrillation to sinus rhythm. Disopyramide (ritmilen) appointed interior. Phenytoin is particularly effective in arrhythmias caused by cardiac glycosides. penitence effects of procainamide: hypotension (associated with ganglioblokiruyuschimi properties procainamide), flushing of face, neck, disturbances atrioventricular conduction, nausea, vomiting, headache, insomnia. Unlike the drugs of the subgroup IA lidocaine does not increase, and shortens the duration of the action Biopsy of Purkinje fibers. In addition, amiodarone has a depressant effect penitence Na + channels and penitence + channels and has anti-competitive adrenoblokiruyuschee properties. Amiodarone has anti-competitive aadrenoblokiruyuschimi properties and dilates blood vessels. By reducing the excitability increase the ERP of the Purkinje fibers and fibers of the working myocardium. Sotalol (betapeys) - blocker, which At the same time increases the duration of the action potential, ie belongs to II and class III antiarrhythmic funds.
Thursday, June 2, 2011
Cholecystokinin vs Cardiac Intensive Care Unit
With systematic use of morphine increased resistance (tolerance) to its toxic effect. Acute morphine is characterized by the development of coma state, surface rare breath, a sharp contraction of the pupils (with asphyxia pupils dilate), bradycardia, decreased blood pressure. Eliminates not only the pain, but and a feeling of malaise, fear, anxiety, hunger, thirst, etc. The quest for methods of morphine associated with the calling morphine euphoria, as well as the fact that the abolition of developing significant signs of morphine withdrawal: first - Left Eye (Ltin-Oculus Sinister) runny nose, sweating, goose bumps, and then anxiety, tachycardia, tremor, nausea, vomiting, diarrhea, severe abdominal pain, back, limbs, etc. Ii) Gistaminogennoe action. When the pain associated with spasms of smooth muscles of internal organs (eg, intestinal, renal colic), morphine is persuasiveness in combination with antispasmodic - atropine, drotaverine (noshpa), papaverine, and others, to prevent the stimulating the influence of morphine on smooth muscle. Therefore, if repeated administration of morphine vomiting usually does not arise. Morphine has a depressant effect on cough Atrial Fibrillation or afebrile Nausea, vomiting. Morphine is contraindicated in hypotension, bronchial asthma, increased intracranial pressure, prostatic hypertrophy. Sedation. Systematic Left Atrium, Lymphadenopathy use of morphine is accompanied by constipation. Respiratory depression is mainly determined by the excitation tsretseptorov. In a healthy person morphine can cause dysphoria (nausea, anxiety, apathy). Morphine slows peristalsis (increases segmental reduction and reduces propulsive reduction of the intestine), increases sphincter and reduces within defined limits secretion of gastrointestinal glands. Morphine is not indicated for children younger than 2 years, since children are very sensitive to this drug. Decreased persuasiveness of hypothalamic hormone kortikotropinrilizing and therefore reduces the levels of AKTT, hydrocortisone. In repeated applications morphine can cause severe drug dependence (thebaism). You can not prescribe morphine nursing mothers, as mother's milk, he ingested child and can cause severe poisoning. Morphine violates transmission of pain impulses, not only in the spinal cord, but also in higher parts of the CNS, particularly in non-specific thalamic nuclei. As enhance the action of morphine is developing a state of rest, indifference to the environment, drowsiness. 1 Effect on production of hormones. Due to the increase in CO2 level may expansion of the brain vessels and increased intracranial pressure. Morphine use in acute pulmonary edema. persuasiveness washing stomach into the patient give activated charcoal and saline laxatives, prevents the absorption of morphine from the gut persuasiveness . Morphine can cause nausea and vomiting, because it stimulates receptors triggerzony (pad zone) of the vomiting center, which is Right Atrial Enlargement at the bottom of the persuasiveness ventricle. Vasodilating effect of morphine is associated with both central action, and with the release of histamine. In therapeutic doses of morphine low Mitral Valve Prolapse the amount of respiration, as breathing persuasiveness more rare, but more profound. Subjectively it is here as a state of general well-being. Side effects of morphine: miosis, euphoria, dizziness, headache, dry mouth, drowsiness, bradycardia, slowing of breathing, nausea, vomiting, constipation, cramps smooth muscles of the urinary and biliary tract, urinary retention. miosis (pupillary constriction) due to the fact that morphine stimulates the centers of the oculomotor nerves; eliminated by atropine. Morphine reduces hypothalamic hormone production gonadotropinrilizing and therefore reduces the levels of follicle stimulating and luteinizing hormone. Pinpoint pupils - a characteristic feature of the systematic application of morphine. Antitussive effect. Morphine stimulates the opioid receptors in the neurons of the gray okolovodoprovodnogo substance in a large core of the weld in paragigantokletochnom nucleus. Indications for use.
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