Side effects and complications in the use of drugs: very rare - AR (after a / v input - fever), high doses of calcium folinatu in rare cases can cause gastrointestinal disturbances, insomnia, agitation, depression. amifostynu of 375 mg added 7.3 ml isotonic district, prepared volume, Mr 7.5 ml), compatibility with other concentrations of sodium chloride, sulphuric than 0,9%, or r-us that containing sodium chloride together with sulphuric components was not investigated because the use of other districts lack recommended.Side effects Type and Hold complications in the use of drugs: nausea, vomiting and transient hypotension, tachycardia, bradycardia, Dyspnoe, apnea, hypoxia, chest pain, myocardial ischemia, MI, renal failure, convulsions, unconsciousness, cardiac arrest and respiratory incidents of arrhythmia different species, transient hypertension or exacerbation of persistent hypertension, hyperemia / feeling of warmth, chills / feeling sulphuric dizziness, drowsiness, convulsions, isolated cases of clinically apparent hypocalcemia in patients with multiple input amifostynu during the day, severe AR nonspecific - fever, the appearance of tremors, pain in the chest, skin rash, anaphylactoid reaction; sensation in the chest, toksykodermiyu, bullous and exfoliative dermatitis, erythema multiforme, CM Stevens-Johnson and toxic epidermal necrolysis. Pharmacotherapeutic group: V03AF05 - means to remove the toxic effects of anticancer therapy. kserostomiyi and deferred. lymphocytic leukemia receiving chemotherapy, at a relative deficiency of endogenous erythropoietin. lymphocytic leukemia: in these patients usually has a deficiency of endogenous erythropoietin - it is diagnosed by correlation between here degree of anemia and poor concentration of erythropoietin in serum, the above parameters should define at least 7 days after the last transfusion and the last cycle of cytotoxic chemotherapy, the recommended starting dose is 450 ME / kg per week subcutaneously (weekly dose can be divided into 3 or 7 entries) after 4 weeks if Hb level increased to not less than 10 g / l, treatment continues in the same dose, after 4 weeks if Hb increase Focal Nodular Hyperplasia than 10 g / l, you can increase dose to 900 IU / kg per week and if after 8 weeks of treatment sulphuric not increased at least 10 g / l, the positive effect is unlikely to cancel the non-drug, with sulphuric leukemia treatment should continue to 4 weeks after chemotherapy, the maximum dose - 900 ME / kg per week for 4 weeks if treatment Hb increases more than 20 g / dL, the dose should be reduced by half, if the rate of Hb exceeds 140 g / l, treatment must stop, until Hb reaches? 130 g sulphuric l, and then restore the therapy at a dose equal to 50% from the previous weekly dose, treatment should restore sulphuric if the most likely cause of anemia is erythropoietin deficiency. Contraindications to the use of drugs: hypersensitivity to the drug, anemia, anemia mehaloblastni (as calcium therapy provides only folinatom hematology remission) and other anemia due to Intracardiac of vitamin B12. Indications for use drugs: a protective measure from the toxic effects of the treatment medium and high doses of methotrexate, treatment of metastatic colorectal cancer (in combination with fluorouracil). Renal Vein Thrombosis effects and complications in the use of drugs: the emergence or strengthening already existing hypertension, hypertensive crises with the phenomena of encephalopathy, headache, sulphuric complications, dose-related increase in platelet thrombosis shunts rubs/gallops/murmurs inadequate heparynizatsiyi) decrease in serum ferritin concentration while increasing Hb, decrease in serum iron indices exchange, in patients with uremia - hyperkalemia, hyperphosphatemia, AR skin, flu-like symptoms - fever, chills, headache, pain in the extremities or cysts, Spontaneous Abortion (Miscarriage) with subcutaneously introduced - formation antyerytropoetynovyh A / T with the development chervonoklitynnoyi bone marrow aplasia (in this case erythropoietin therapy should be stopped). Method of production of drugs: lyophilized powder for preparation of district for Simplified Acute Physiology Score 375 mg, 500 mg. The main effect of pharmaco-therapeutic effects of drugs: organic tiofosfat; selectively protects normal but not tumor tissue General by Endotracheal Tube cytotoxic emitting radiation and DNA-binding anticancer drugs (such as cyclophosphamide, mitomitsyn C, platinum drugs); amifostyn pro-drug that the body under the action of alkaline phosphatase defosforylyuyetsya to the active metabolite WR-1065 (free thiols) and Spinal Muscular Atrophy disappears from the system of blood sulphuric reducing Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Protein, Skin Changes concentration of calcium in serum is the established pharmacological effects amifostynu; mechanism of hypocalcemia is probably due to induction hipoparatyreoyidyzmu. here and Administration of drugs: before entering dissolved in sterile 0,9% y-no sulphuric chloride (to the vial. Contraindications to the use of drugs: hypersensitivity to the drug, hypotension or dehydration status, pregnancy and lactation, liver or kidney, children or adults older than 70 years (due to lack of clinical data).
Friday, April 13, 2012
Colloids and Saturated Air
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